CAT scans of brain

Hot spots of disease: The human connectome as a biomarker for brain disorders

Principal investigator: Dr Martijn van den Heuvel
Location: Netherlands
Research award: Fellows Award
Funding Period: 2016-2019

Can patterns in the brain show the differences between mental health conditions – and speed up diagnosis and treatment?

The project

Many mental health conditions share similar symptoms, which can be a big barrier to quick, accurate diagnosis.

People are left waiting for a condition to be identified or are misdiagnosed. In both cases, the wait for effective treatment can be a long one.

So Martijn and his team are taking a fresh approach to analysing the similarities and differences between mental health conditions.

The process

By mapping activity between different areas of the brain in various mental health conditions, our researchers are hoping to identify patterns that are specific to single conditions and others that overlap.

That new knowledge would help to improve diagnosis, as well as increasing understanding of shared symptoms common to multiple mental health problems.

The potential

This project involves a new approach to understanding the similarities and differences between mental health conditions.

Advances in this area are vital if we are to accurately understand the nature of different conditions, and so inspire better diagnoses, better treatment and better outcomes.

Dr Martijn van den Heuvel

Dr Martijn van der Heuvel works at the UMC Utrecht Brain Centre Rudolf Magnus in the Netherlands. He focuses on providing new insight into the rules that drive structural and functional brain networks.

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