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  • 1 in 10 people are affected by depression in the UK
  • By 2030depression is predicted to be the world’s biggest health problem
  • Only £1.55 is spent on research each year for every person affected in the UK

What is depression?

We all experience low mood sometimes - it is a normal part of life especially after a loss or bereavement. Depression in the medical sense however can leave people feeling severely sad, empty, hopeless or guilty for weeks, months or even years. 

It can affect every part of a person’s life. Relationships. Work. Physical health. They all suffer. And, at its most severe, it can be life-threatening.

Depression can also have physical symptoms, such as fatigue, sleeping badly or much more than usual, poor appetite or overeating, and loss of sex drive.

Everyone experiences depression differently. But however it affects people, it’s definitely not the same as simply feeling low for a few days or something that people can ‘snap out of’.

Help tackle depression

Join thousands of others in transforming mental health

Uncovering the priorities for depression research

There’s so much we don’t know about what causes depression, how we can prevent it and which treatments work best. Research is essential to answering these questions.

To focus our work, we asked 3,000 people with depression what research answers would make the biggest difference to their lives. Their answers highlighted preventing the occurrence and recurrence of depression as the highest priority.

Our research into depression


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Need help?

Get information and advice on anxiety disorder at NHS Choices. If you're having a mental health emergency find out who to turn to using our urgent help and advice resource.

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